Food and Behaviour Research

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Aspartame intake is associated with greater glucose intolerance in individuals with obesity

Kuk JL, Brown RE. (2016) Appl Physiol Nutr Metab. 24 1-4. [Epub ahead of print] 

Web URL: View this and related abstracts via PubMed here.


This study examined whether sucrose, fructose, aspartame, and saccharin influences the association between obesity and glucose tolerance in 2856 adults from the NHANES III survey.

Aspartame intake significantly influenced the association between body mass index (BMI) and glucose tolerance (interaction: P = 0.004), wherein only those reporting aspartame intake had a steeper positive association between BMI and glucose tolerance than those reporting no aspartame intake.

Therefore, consumption of aspartame is associated with greater obesity-related impairments in glucose tolerance.