Food and Behaviour Research

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Vitamin D Deficiency, Its Role in Health and Disease, and Current Supplementation Recommendations

Pfotenhauer KM, Shubrook JH (2017) J Am Osteopath Assoc. 2017 May 1;117(5): 301-305. doi: 10.7556/jaoa.2017.055 

Web URL: Read this and related abstracts on PubMed here


Vitamin D deficiency has been identified as a common metabolic/endocrine abnormality. Despite known dietary sources of vitamin D and the role of sunlight in its production, much of the US population may have inadequate levels of serum 25-hydroxyvitamin D. Deficiency of vitamin D can be caused by a variety of health conditions, but studies on the effects of vitamin D supplements have had mixed results.

This evidence-based clinical review discusses what is currently known about vitamin D and what areas need further research to clarify its role in health and disease.