Food and Behaviour Research

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Avocado Consumption Increases Macular Pigment Density in Older Adults

Scott TM, Rasmussen HM, Chen O, Johnson EJ (2017) Nutrients.  2017 Aug 23;9(9).  pii: E919. doi: 10.3390/nu9090919. 

Web URL: Read this and related abstracts on PubMed here


Lutein is selectively incorporated into the macula and brain. Lutein levels in the macula (macular pigment; MP) and the brain are related to better cognition. MP density (MPD) is a biomarker of brain lutein. Avocados are a bioavailable source of lutein.

This study tests the effects of the intake of avocado on cognition. This was a six-month, randomized, controlled trial. Healthy subjects consumed one avocado (
n = 20, 0.5 mg/day lutein, AV) vs. one potato or one cup of chickpeas (n = 20, 0 mg/day lutein, C). Serum lutein, MPD, and cognition were assessed at zero, three, and six months.

Primary analyses were conducted according to intent-to-treat principles, with repeated-measures analysis. At six months, AV increased serum lutein levels by 25% from baseline (
p = 0.001). C increased by 15% (p = 0.030). At six months, there was an increase in MPD from baseline in AV (p = 0.001) and no increase in C. For both groups, there was an improvement in memory and spatial working memory (p = 0.001; p = 0.032, respectively).

For AV only there was improved sustained attention (
p = 0.033), and the MPD increase was related to improved working memory and efficiency in approaching a problem (p = 0.036).

Dietary recommendations including avocados may be an effective strategy for cognitive health.