Food and Behaviour Research

Donate Log In

Role of Magnesium in Vitamin D Activation and Function

Anne Marie Uwitonze AM, Razzaque MS (2018) Journal of the American Osteopathic Association March 2018, 118 181-189. doi:10.7556/jaoa.2018.037 

Web URL: Read the abstract and full research on jaoa.org here

Abstract:

Nutrients usually act in a coordinated manner in the body. Intestinal absorption and subsequent metabolism of a particular nutrient, to a certain extent, is dependent on the availability of other nutrients.

Magnesium and vitamin D are 2 essential nutrients that are necessary for the physiologic functions of various organs. Magnesium assists in the activation of vitamin D, which helps regulate calcium and phosphate homeostasis to influence the growth and maintenance of bones. All of the enzymes that metabolize vitamin D seem to require magnesium, which acts as a cofactor in the enzymatic reactions in the liver and kidneys.

Deficiency in either of these nutrients is reported to be associated with various disorders, such as skeletal deformities, cardiovascular diseases, and metabolic syndrome. It is therefore essential to ensure that the recommended amount of magnesium is consumed to obtain the optimal benefits of vitamin D.

FAB RESEARCH COMMENT:

See the associated news article: