Anstey KJ, Peters R (2019) J Alzheimers Dis. Sep 2019;70(s1): S1-S3. doi: 10.3233/JAD-190506.
In this special issue from the International Research Network on Dementia Prevention (IRNDP), we present new research from around the globe examining the potential risk factors for dementia. We report on some of the ongoing and crucial risk reduction trials and highlight some of the population level considerations and the remaining evidence gaps.
In a comprehensive umbrella review of systematic reviews, Anstey and colleagues summate the observational evidence on risk factors for Alzheimer’s disease, vascular dementia, and any dementia, and highlight the lack of evidence for many risk factor exposures in midlife, a lack of data on risk factors for vascular dementia and from low and middle income countries.