FAB RESEARCH COMMENT:
Foods and diets high in fructose have long been linked with metabolic problems including non-alcoholic fatty liver disease, Type 2 diabetes and obesity.
This study shows for the first time that fructose can also cause immune system changes that promote inflammation - which is associated with these and other 'non-communicable diseases'.
Inflammation also affects brain development and function, and excessive or chronic inflammation is linked with many developmental and mental health conditions, including ADHD and autism, depression, and dementia.
Fructose makes up half of ordinary table sugar, and a slightly higher proportion of high fructose corn syrup.
Fructose is also found in fruits and sweet vegetables, but when consumed in these natural, whole foods - in moderation - it is not considered to be problematic for most people, as
(1) the dietary fibre in these foods slows its release, and also prevents over-consumption by regulating appetite, and
(2) the many important nutrients found in vegetables and fruits also help to protect against negative effects
By contrast, abundant evidence indicates that the high fructose content of ultra-processed foods and many soft drinks (as found in typical modern western-type diets) - IS a major contributor to physical and mental ill-health.
This study provides yet another potential mechanism by which high fructose intakes from these sources can damage health.
For the related research article please see:
And for another recent and important insight into the negative effects of fructose, as consumed in ultra-processed sugary foods and drinks, see also:
For further information on this topic, please see the following lists, which are regularly updated: