FAB RESEARCH COMMENT:
This randomised controlled trial - the gold standard study design for investigating causal effects
- found preliminary evidence that probiotic supplementation vs placebo may be of benefit in some children with ASD.
Findings differed between children with and without major gastrointestinal (GI) symptoms, as core (behavioural) ASD symptoms were significantly reduced only in the latter group, while probiotics reduced both sensory and GI symptoms in the latter.
As the researchers emphasised, more research is needed, but these findings add to the increasing evidence that gut microbial imbalances can affect brain function and behaviour, as well as gut and immune health (all of which are fundamentally inter-related).
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