Food and Behaviour Research

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18 Sept 2012 - NutraIngredients - Maternal vitamin D backed to help build better baby brain

by Nathan Gray

Mothers with low levels of vitamin D are more likely to have children with slower brain development and lower mental and motor skills, warn researchers

FAB RESEARCH COMMENT:

This study adds to the growing evidence that Vitamin D deficiency during pregnancy predicts poorer outcomes for the cognitive and motor development of the resulting children.

For details of this study, see

For a list of further references on the importance of Vitamin D deficiency to brain development in both humans and animal models, see:

Mothers with low levels of vitamin D are more likely to have children with slower brain development and lower mental and motor skills, warn researchers

The population-based study investigated the association between maternal vitamin D levels and their children's development in over 1,800 expectant mothers and babies.

Writing in the journal Pediatrics, the Spanish research team reveal that low plasma levels of Vitamin D (25(OH)D3) in the first trimester of pregnancy in mothers-to-be were associated with babies who showed reduced brain development and motor skills.

“Higher circulating concentration of maternal 25(OH)D3 in pregnancy was associated with improved mental and psychomotor development in infants,” explained the research team – led by Dr. Eva Morales, from the Center for Research in Environmental Epidemiology, Spain.

Study details

The data showed that 20% of the women were vitamin D-deficient and another 32% had insufficient levels of the vitamin. The researchers revealed that the babies of mothers whose prenatal vitamin D level was deficient scored around 2.6 points lower on a mental test and 2.3 points lower on psychomotor tests at the age of 14 months when compared to the children of women who had adequate vitamin D levels.

After adjustment for potential confounders, infants of mothers with 25(OH)D3 concentrations in pregnancy more than 30 ng/mL showed higher mental score and higher psychomotor score in comparison with those of mothers with 25(OH)D3 concentrations less than 20 ng/mL. The team added that a linear relationship between maternal 25(OH)D3 status and mental and psychomotor scores in the offspring was found.

Morales noted that differences of four and five points in such neurological tests could result in a halving of the number of children with above-average IQ scores (defined as above 110 points).