Chiu, C.C., Huang, S.Y., Shen, W.W., Su, K.P. (2003) Am J Psychiatry. 160(2) 385.
Letter - no abstract available
Excerpt from the introduction to this case report
Depression during pregnancy affects both the mother and the child. Most drugs pass from mother to baby through the placenta in different degrees. Medicating depressed pregnant patients is a clinical dilemma. Omega-3 polyunsaturated fatty acids, with a possible antidepressant effect and a lack of teratogenicity for the fetus, seem to be a favorable treatment alternative. We report here what is to our knowledge the first case of successful treatment with omega-3 polyunsaturated fatty acid monotherapy of a pregnant patient with major depressive disorder.