FAB RESEARCH COMMENT:
These findings show that opioid-like peptides arising from the digestion of the common food proteins
gluten (
found in wheat and many other grains) and
A1 beta-casein (
found in ordinary cows' milk) can:
1) reduce the uptake by brain and gut cells of cysteine, needed to make glutathione (important for antioxidant defences), and
2) affect gene expression in ways that may have important developmental consequences.
As the researchers point out, these effects may have relevance to autism and other developmental conditions, and may help to explain the reported benefits for
some individuals of diets free from gluten and casein.
The A2 form of beta-casein found in human breastmilk (and other mammal milks) did not produce the same effects. This may help to explain why at least some individuals who react badly to cows' milk nonetheless appear to be able to tolerate milk and dairy products derived from other animals, such as such as goats or sheep, which - like human breastmilk - contain the A2 rather than the A1 form of beta-casein.
Read the related news article here:
See also the following events, featuring FAB Research presentations from the lead author, Malav Trivedi:
'Questioning answers' blogspot discussion of the research paper can be found
here
And for more information on the differences between A1 and A2 beta-casein, see: