Recent developments in human health science now suggest that being physically fit almost certainly improves our longevity.
In very simple terms, human fitness can broadly be separated into two facets – aerobic fitness and strength. Aerobic fitness can be assessed with the dreaded VO2max test, which involves exercising to your physical limit on a treadmill or stationary bike. This gives a good indication of the functional capacity of an individual’s cardio-respiratory system.
Strength assessments are neither so gruelling nor simple, but usually involve producing maximum muscle contractions using weights or a force measurement device like a stationary force transducer or a grip dynamometer. Both the aerobic and strength tests have now been proven to be excellent predictors of life span. This means that individuals who are most aerobically fit or most strong are most likely to live the longest.
The physical frailty associated with ageing is primarily due to reduced aerobic capacity and physical strength. After the age of 25, inactive individuals lose their aerobic capacity at a rate of approximately 1%/year. They lose muscle mass at a rate of approximately 0.6%/year after the age of around 30 (30% decrease from age 30 to 80).
As this implies, not everyone loses muscle mass and aerobic capacity at the same rate. Veteran or masters athletes are a particularly interesting segment of the population in this regard. They have an incredible ability to retain their muscle mass and function well into old age. This may be the result of genetic advantages which lead these individuals to self-select to be active. But it is just as likely that their athletic activities are somehow preserving their fitness.
Studies into immobilisation and reduced activity support this idea that ageing-related declines in fitness may have much to do with doing less physical activity than age per se. One recent study found that simply reducing the step count of healthy older adults for two weeks is sufficient to reduce the lean mass of the legs (mostly muscle) by almost 4%, for example.
Another study showed that when healthy young adults have one leg completely immobilised for two weeks, it leads to a 5% decrease in muscle area and a shocking 25% decrease in muscle strength. In short, the old “use it or lose it” adage is highly applicable to physical fitness. This is particularly poignant when you consider that the aerobically fittest and strongest men in a population are 60% less likely to die of any cause than the weakest and least aerobically fit. You start to see why the American College of Sports Medicine launched the “Exercise is Medicine” initiative as a way to increase the use of exercise as a way to promote health a few years ago.
There is now such a large body of evidence on the negative health effects of being physically inactive that a team of researchers has even conservatively quantified the associated disease burden and death rates. They estimated that in 2008, inactivity caused a whopping 9% of all premature deaths.
It is worth pointing out here that it is extremely difficult to truly delineate cause from effect – the data tells us that fitness correlates with longevity, but it may not be the actual cause. A number of studies have now shown that the ability of exercise to improve fitness is highly variable, with some individuals being described as “non-responders” and a very small percentage even displaying negative health outcomes from exercise.
But the key question is, “does increasing fitness improve longevity?” A large follow-up study in which men had their aerobic fitness tested at least twice over the course of five years seems to suggest that for aerobic fitness at least, the answer is yes. The study found that a group of men who became fit had a significantly lower risk of dying than a group who stayed unfit. We don’t have equivalent data for strength training in the general population yet, but recent data certainly suggests that strength training during cancer survival is associated with a reduced risk of death from all causes.
Even the very elderly can substantially improve their physical function with a programme of physical training. Even though they will start out at a lower baseline for strength and aerobic fitness than younger people, they can actually achieve similar degrees of improvement with an effective training programme. Being classified as fit at some point in middle age is meanwhile associated with a reduced risk of death even if you become unfit later. Then there is the so-called “fit-fat” phenomenon, which is that fitness can offset the mortality risk of being overweight or obese. Even for those who remain obese afterwards, the exercise and healthy diet will still significantly improve their cardio-respiratory health.
The final take-home message: so long as it is safe to do so, most people should experience gains in health and longevity from beginning (and sticking to) a programme of exercise designed to get them stronger and more aerobically fit. This is irrespective of age or fatness. However much you over-indulge from the comfort of your sofa this festive season, when the time for self-improvement comes around in January, there is still hope for us all.