Food and Behaviour Research

Donate Log In
Advanced Search

Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study.

Amminger GP, Schafer MR, Schlogelhofer M, Klier CM, McGorry PD. (2015) Nature Communications 11;6 7934. doi: 10.1038/ncomms8934. 

Web URL: View this and related abstracts via PubMed here. Free full text of this article is available online

Abstract:

Long-chain omega-3 polyunsaturated fatty acids (PUFAs) are essential for neural development and function. As key components of brain tissue,omega-3 PUFAs play critical roles in brain development and function, and a lack of these fatty acids has been implicated in a number of mental health conditions over the lifespan, including schizophrenia.

We have previously shown that a 12-week intervention with omega-3 PUFAs reduced the risk of progression to psychotic disorder in young people with subthreshold psychotic states for a 12-month period compared with placebo. We have now completed a longer-term follow-up of this randomized, double-blind, placebo-controlled trial, at a median of 6.7 years.

Here we show that brief intervention with omega-3 PUFAs reduced both the risk of progression to psychotic disorder and psychiatric morbidity in general in this study. The majority of the individuals from the omega-3 group did not show severe functional impairment and no longer experienced attenuated psychotic symptoms at follow-up.

FAB RESEARCH COMMENT:

Free full text of this article is available from the website of Nature here

And for an accessible summary of this research, please see the associated news articles:
For details of the original 12-month study involving these young people, all of whom were originally judged to be at very high risk for developing psychosis, see also:

Food and Behaviour Research is a registered charity (No SC034604) and a company limited by guarantee (Co No SC 253448)

Newsletter Signup

Sign up here to receive our free newletters.

Useful Links

Contact Us

FAB Research 
23 Carlton Road
Oxford
OX2 7SA

Important Notice

Medical opinion and guidance should always be sought for any symptoms that might possibly reflect a known or suspected disease, disorder or medical condition. Information provided on this website (or by FAB Research via any other means) does not in any way constitute advice on the treatment of any medical condition formally diagnosed or otherwise.

Site by Redstone Websites. Easy to Use Web Content Management. 2022 © All Rights Reserved.